germinal centre meaning in Hindi

Examples

1. CD23 can also be demonstrated in germinal centre B-cells using immunohistochemistry, but it is not present in the resting cells of the surrounding mantle zone.
2. It is characterized by white lumps in the undersurface of the upper eyelid ( conjunctival follicles or lymphoid germinal centres ) and by non-specific inflammation and thickening often associated with papillae.
3. Using immunohistochemistry, CD57 molecule can be demonstrated in around 10 to 20 % of lymphocytes, as well as in some germinal centres of lymph nodes, tonsils, and the spleen.
4. CR1, a surface protein produced primarily by follicular dendritic cells, appears to be critical for generation of appropriately activated B cells of the germinal centre and for mature antibody responses to bacterial infection.
5. In the case of clearance deficiency, apoptotic nuclear debris accumulates in the light zone of GC and gets attached to FDC . This serves as a germinal centre survival signal for autoreactive B-cells.
6. Most of the monocytes and tingible body macrophages ( TBMs ), which are found in the germinal centres of lymph nodes, even show a definitely different morphology; they are smaller or scarce and die earlier.
7. "' Progressive transformation of germinal centres "', abbreviated "'PTGCs "'and also "'progressive transformation of germinal centers "', is a reactive lymph node process of undetermined etiology.
8. BAFF stimulates aberrant B-cell maturation, leading to the emergence of self-reactive B cells, which locally produce autoantibodies, in a germinal centre-like structure ( GC-like ), which is also the location of lymphomagenesis ( origin of lymphoma ).